Will AI replace radiation oncologists? What are the best treatment options for patients with operable gastroesophageal adenocarcinoma?
Our Host Rachael Babin chats to radiation oncologist Eugene Koay and medical oncologist Lizzy Smyth, both of whom were international guest speakers at the AGITG meeting in November 2022.
Eugene gives our listeners the low down on the latest AI developments, big data, dose escalation and radiomics. Lizzy walks us through a recap of international collaborative research projects, surgery free approaches in upper GI cancers and the future of immunotherapy in GI, including CAR T in solid tumours.
There’s so much analysis and quite a few giggles packed into this short episode.
This is a fascinating, informative and fun episode of Experts on Point, brought to you by The Oncology Podcast. We hope you enjoy listening.
Papers and Resources:
Adding radiation to systemic therapy extends overall survival for patients with advanced liver cancer. ASTRO Press Release, October 24, 2022. Access online here.
Reyngold M, et al. Association of Ablative Radiation Therapy With Survival Among Patients With Inoperable Pancreatic Cancer. JAMA Oncol. 2021;7(5):735–738. doi:10.1001/jamaoncol.2021.0057. Access online here.
Tao R, et al. Ablative Radiotherapy Doses Lead to a Substantial Prolongation of Survival in Patients With Inoperable Intrahepatic Cholangiocarcinoma: A Retrospective Dose Response Analysis. J Clin Oncol. 2016 Jan 20;34(3):219-26. doi: 10.1200/JCO.2015.61.3778. Epub 2015 Oct 26. Erratum in: J Clin Oncol. 2019 Apr 10;37(11):942. PMID: 26503201; PMCID: PMC4980564. Access online here.
Singhi AD, et al. Early Detection of Pancreatic Cancer: Opportunities and Challenges. Gastroenterology. 2019 May;156(7):2024-2040. doi: 10.1053/j.gastro.2019.01.259. Epub 2019 Feb 2. PMID: 30721664; PMCID: PMC6486851. Access online here.
This Week’s Team:
Associate Professor Eugene Koay
Eugene Koay
Dr. Koay is an Associate Professor in the Department of Gastrointestinal (GI) Radiation Oncology at MD Anderson Cancer Center. Dr. Koay treats all types of GI cancers. He is well-recognised for his clinical and translational research on GI cancers and their properties on diagnostic imaging, participating in national and international collaborations at the forefront of science. He has published over 140 articles, and a textbook titled An Introduction to Physical Oncology. He enjoys educating the next generation and has given lectures at multiple undergraduate, graduate, medical, health professional and resident courses. He has mentored dozens of students, residents, and fellows over the past decade, helping them achieve successful presentations, publications, and awards.
You can find Eugene on Twitter here: @eugenekoay
Lizzy Smyth
Elizabeth (Lizzy) Smyth is an consultant in gastrointestinal oncology at Addenbrooke’s Hospital in Cambridge. Dr Smyth commenced her oncology training in Dublin, Ireland. In 2009 she was awarded an Irish Society of Medical Oncology fellowship to train at Memorial Sloan-Kettering Centre, New York. Following this she worked at the Royal Marsden Hospital in London from 2011-2018. Her research focus is on clinical trials and translational research in gastroesophageal cancer and she has worked on trial design and management of national and international trials. She is a member of the European Society of Medical Oncology Faculty GI educational faculty and in 2017 was elected as secretary of the EORTC GI clinical trials group for the period 2018-2021. Dr Smyth is committed to furthering national and international collaboration in GI trials research.
You can find Lizzy on Twitter here: @LizzySmyth1
Rachael Babin
Rachael Babin is Host of The Oncology Podcast, Editor-in-Chief of The Oncology Newsletter, and Publisher of Oncology News Australia and The Oncology Network.
With a background in oncology communications and academic publishing, Rachael is happiest sitting behind the mic chatting to interesting people about the impact their work makes in oncology.
Connect with us on Twitter here: @OncologyNewsAus
