Recent research has uncovered a significant pathway for microplastic (MP) entry into the human body: intravenous (IV) infusions.
A study published in Environment & Health., has revealed that IV infusions administered from polypropylene (PP) plastic bottles can introduce approximately 7,500 PP particles per litre into the bloodstream.
These MPs range in size from 1 to 62 micrometres, with a median size of about 8.5 micrometres. Notably, around 90% of these particles are between 1 and 20 micrometres, and approximately 60% fall within the 1 to 10 micrometre range.
Potential Health Implications
The direct introduction of MPs into the circulatory system raises concerns about their potential deposition in various organs and the subsequent clinical effects. While the full extent of health risks associated with MPs in the bloodstream is still under investigation, this study emphasises the need for healthcare professionals to be aware of this exposure route.
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Recommendations for Healthcare Practice
Given these findings, medical practitioners should consider the following steps to mitigate MP exposure during IV therapy:
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Evaluate Infusion Materials: Assess the materials used for IV infusions and consider alternatives to PP plastic bottles when feasible.
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Enhance Filtration Techniques: Implement or improve filtration methods to reduce particle contamination in IV solutions.
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Stay Informed: Keep abreast of ongoing research regarding MPs in medical settings to make informed decisions about patient care.
This study underscores the importance of scrutinising medical equipment and procedures to minimize unintended health risks. As research progresses, continued vigilance and adaptation of best practices will be crucial in safeguarding patient health against emerging contaminants like microplastics.
Paper: Huang, T., et al. MPs Entering Human Circulation through Infusions: A Significant Pathway and Health Concern. Environ. Health 2025, Published February 14, 2025. https://doi.org/10.1021/envhealth.4c00210
