S4 E1: Hot Flushes, Aspirin and AI

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The Oncology Journal Club Podcast hosted by Professor Craig Underhill, Dr Kate Clarke and Professor Chris Jackson | Proudly Produced by The Oncology Network

In today’s episode, we explore practical wins and bold ideas across supportive care, colorectal cancer prevention, immunotherapy timing, digital triage and equity. From halving hot flushes with an NK1/NK3 blocker to biomarker-guided aspirin in colon cancer, we weigh value, risk and what truly improves lives.

• Elinzanetant cutting severe hot flushes and improving treatment adherence
• Current non-hormonal options and gaps in symptom control
• Biomarker-selected aspirin reducing recurrences in colorectal cancer
• Limits of DFS, toxicity trade-offs and subgroup signals
• Rising early-onset colorectal cancer and system planning needs
• Possible environmental and microbiome drivers under study
• ASCO geriatric assessment guidance and G8 screening in clinics
• PD-1 with short-course radiotherapy boosting rectal pCR rates
• Large language models for safe, efficient symptom triage
• Rare cancers report on access, cost, and rural inequities
• Telehealth standards to link expertise closer to home
• Healthy workplace culture to retain a resilient oncology workforce

Physicians, don’t forget you can claim CME points for listening to the show!

With thanks to our Editor, Graham Knowles.

To Access all papers and resources discussed in this podcast, please click here

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