The Oncology Journal Club: Episode 9

Pinterest LinkedIn Tumblr +

Curious about the latest breakthroughs in oncology treatment? Prepare to have your perspective shifted and hopefully a few laughs too, as we dissect the most compelling research and clinical insights with our expert hosts, Professor Craig Underhill, Dr. Kate Clarke, and Professor Christopher Jackson.

How can patient-reported outcomes (PROMs) offer benefits comparable to early palliative care referrals? Craig takes us through the latest meta-analysis.

Can oral cannabis extract play a role in managing chemotherapy-induced nausea and vomiting? Kate presents new Australian data.

What if understanding the nuances of T3 extension could revolutionise the management of locally advanced rectal cancer? CJ unpacks the latest ASCO Guidelines.

About The Oncology Journal Club:

We have taken an old concept and updated it with a new format. In each episode, a team of expert contributors will review topical journal papers and interview special guests who are leaders in their fields to help keep you informed of the latest developments on the go.

We hope you enjoy listening and find this a valuable and entertaining resource.



PAPERS:

CJ:

Aaron J. Scott et al., Management of Locally Advanced Rectal Cancer: ASCO Guideline. JCO 0, JCO.24.01160. Access online here.

Kate:

Grimison P, et al. Oral Cannabis Extract for Secondary Prevention of Chemotherapy-Induced Nausea and Vomiting: Final Results of a Randomized, Placebo-Controlled, Phase II/III Trial. J Clin Oncol. 2024 Aug 16:JCO2301836. doi: 10.1200/JCO.23.01836. Epub ahead of print.  Access online here.

Craig: Balitsky AK, et al. Patient-Reported Outcome Measures in Cancer Care: An Updated Systematic Review and Meta-Analysis. JAMA Netw Open. 2024 Aug 1;7(8):e2424793. doi: 10.1001/jamanetworkopen.2024.24793.  Access online here.

QUICKBITES:

Kate:

  1. Trikha M, et al. Performance of Low-Dose Immunotherapy and Standard-Dose Immunotherapy in Microsatellite Instability-High Metastatic Colorectal Cancer: Real-World Data (CLouD-High Study). JCO Glob Oncol. 2024 Aug;10:e2400141. doi: 10.1200/GO.24.00141. PMID: 39159410. Access online here.
  2. Meyer ML, et al. New promises and challenges in the treatment of advanced non-small-cell lung cancer. Lancet. 2024 Aug 6:S0140-6736(24)01029-8. doi: 10.1016/S0140-6736(24)01029-8. Epub ahead of print. PMID: 39121882. Access online here.

Craig:

  1. Klatte DCF, et al. Utilization and Outcomes of Multigene Panel Testing in Patients With Pancreatic Ductal Adenocarcinoma. JCO Oncol Pract. 2024 Aug;20(8):1081-1090. doi: 10.1200/OP.23.00447. Epub 2024 Apr 15.  Access online here.
  2. van Not OJ, et al. Long-Term Survival in Patients With Advanced Melanoma. JAMA Netw Open. 2024 Aug 1;7(8):e2426641. doi: 10.1001/jamanetworkopen.2024.26641. Access online here.

Chris:

  1. Wang J, et al. Impact of Preoperative Time Intervals for Neoadjuvant Chemoradiotherapy on Short-term Postoperative Outcomes of Esophageal Cancer Surgery: A Population-Based Study Using the Dutch Upper Gastrointestinal Cancer Audit (DUCA) Data. Ann Surg. 2024 Aug 8. doi: 10.1097/SLA.0000000000006476. Epub ahead of print. PMID: 39114904. Access online here.
  2. Devin Schellenberg, D, et al. Stereotactic Ablative Radiotherapy for Oligoprogressive Cancers: Results of the Randomized Phase II STOP Trial. International Journal of Radiation Oncology*Biology*Physics. 2024. Access online here.


HOSTS:

Craig Underhill

Professor Craig Underhill

Professor Craig Underhill completed his Bachelor of Medicine and Surgery in 1987 at Melbourne University. He completed medical oncology training in Melbourne and worked as the Senior Clinical Research Registrar at Guy’s Hospital, London.

In 1998 arrived in Albury-Wodonga and established a medical oncology practice and clinical trials unit which has developed expertise and infrastructure to ensure the initiation of high quality trials. The research Unit lead by Dr Underhill has twice been awarded NSW Premier’s Award for Innovation in Cancer Clinical Trials, the inaugural award in 2009 and then again in 2012.

Dr Underhill is the VCCC Regional Oncology Lead and advocates for the increased access to clinical trials for regional Victorians and leads the VCCC teletrials program.

You can find Craig on X/Twitter here: @CraigUnderhill

Kate Clarke

Dr. Kate Clarke

Dr Kate Clarke (MBChB (Otago), FRACP) is a proud New Zealander with a real love for beautiful Aotearoa. Dr Clarke continues to work at being Tangata Tiriti. Much of her research and patient advocacy has an equity focus.  Dr Clarke is grateful to her patients, students, whanau and colleagues for the knowledge and awhi they share.  Ehara taku toa, he takitahi, he toa takitini.

Dr Clarke completed her medical training in Otago, Wellington and London. She has a holistic approach and is passionate about patient-centred care, and believes patients can and should play an active role in their healthcare. Her clinical experience covers a broad range of solid tumour malignancies with special clinical interest in colorectal cancer, upper gastrointestinal cancers and breast cancer.

Chris ‘CJ’ Jackson

Professor Christopher Jackson

Chris Jackson is Professor of Medical Oncology at the University of Otago, Dunedin, and a medical oncologist at Dunedin Hospital and Mercy Cancer Care. He specialises in GI cancers and melanoma, teaches medical students and specialists-in-training, and is heavily involved in both national and international cancer policy, leadership and research.

He was previously the medical director of the Cancer Society of NZ, and his advocacy led to the funding of new cancer drugs, to the development of a new national cancer plan, and to the birth of the national cancer agency Te Aho o Te Kahu.  He currently chairs the agency’s clinical committee and serves on the advisory board. In addition, he is on the programme board of the International Cancer Benchmarking Project, and is a founding member of the Common Sense Oncology movement.

Chris is a self-confessed Radiohead tragic, and recent convert to Crossfit (even though you didn’t ask).

Connect with CJ on X/Twitter: @drkiwicj

PRODUCER:

Rachael Babin

Rachael Babin is Host of The Oncology Podcast, Editor-in-Chief of The Oncology Newsletter,  and Publisher of Oncology News Australia and The Oncology Network.

With a background in oncology communications and academic publishing, Rachael is happiest sitting behind the mic chatting to interesting people about the impact their work makes in oncology.

Connect on Twitter: @OncologyNewsAus

Share.

About Author

The ONA Editor curates oncology news, views and reviews from Australia and around the world for our readers. In aggregated content, original sources will be acknowledged in the article footer.

Leave A Reply

This site uses Akismet to reduce spam. Learn how your comment data is processed.