The Oncology Network is proud to produce this episode of The Oncology Journal Club podcast with you.
Our Host Professor Craig Underhill has a great interview on onco-burnout. Dr Kate Clarke talks us through breast cancer highlights from 2023 and Professor Christopher Jackson gets stuck into Prophylactic Radiation Therapy for High-Risk Asymptomatic Bone Metastases.
We also have a fascinating selection of quick bites with the usual high-level analysis and entertaining banter.
About The Oncology Journal Club:
We have taken an old concept and updated it with a new format. In each episode, a team of expert contributors will review topical journal papers and interview special guests who are leaders in their fields to help keep you informed of the latest developments on the go.
We hope you enjoy listening and find this a valuable and entertaining resource.
PAPERS:
Nindra U, Shivasabesan G, Mellor R, et al Evaluating Systemic Burnout in Medical Oncology Through a National Oncology Mentorship Program. JCO Oncol Pract. 2024 Jan 30:OP2300469. doi: 10.1200/OP.23.00469. Epub ahead of print. PMID: 38290086. Access online here.
Cardoso MJ, Poortmans P, Senkus E, et al. Breast cancer highlights from 2023: Knowledge to guide practice and future research. Breast. 2024 Jan 27;74:103674. doi: 10.1016/j.breast.2024.103674. Epub ahead of print. PMID: 38340683. Access online here.
Gillespie EF, Yang JC, Mathis NJ, et al. Prophylactic Radiation Therapy Versus Standard of Care for Patients With High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Clinical Trial. J Clin Oncol. 2024 Jan 1;42(1):38-46. doi: 10.1200/JCO.23.00753. Epub 2023 Sep 25. PMID: 37748124; PMCID: PMC10730067. Access online here.
QUICK BITES
Toni K. Choueiri et al., Overall survival results from the phase 3 KEYNOTE-564 study of adjuvant pembrolizumab versus placebo for the treatment of clear cell renal cell carcinoma (ccRCC).. JCO 42, LBA359-LBA359(2024). DOI:10.1200/JCO.2024.42.4_suppl.LBA359. Access online here.
Bajorin DF, Witjes JA, Gschwend JE, et al. Adjuvant Nivolumab versus Placebo in Muscle-Invasive Urothelial Carcinoma. N Engl J Med. 2021 Jun 3;384(22):2102-2114. doi: 10.1056/NEJMoa2034442. Erratum in: N Engl J Med. 2021 Aug 26;385(9):864. PMID: 34077643; PMCID: PMC8215888. Access online here.
Cook S, Samuel V, Meyers DE, et al. Immune-Related Adverse Events and Survival Among Patients With Metastatic NSCLC Treated With Immune Checkpoint Inhibitors. JAMA Netw Open. 2024 Jan 2;7(1):e2352302. doi: 10.1001/jamanetworkopen.2023.52302. PMID: 38236598; PMCID: PMC10797458. Access online here.
ASCO Gastrointestinal Cancers Symposium. CheckMate 8HW: Nivolumab Plus Ipilimumab in MSI-High/dMMR Metastatic Colorectal Cancer. Access online here. (Yet to be published)
Mahmoud M.G. Yousef et al., Understanding causes of racial/ethnic survival disparity in 47,178 patients with colorectal cancer: A quantitative evaluation of molecular, socioeconomic, and clinical covariates.. JCO 42, 20-20(2024). DOI:10.1200/JCO.2024.42.3_suppl.20. Access online here.
RESOURCES
Craig Underhill
Professor Craig Underhill
Professor Craig Underhill completed his Bachelor of Medicine and Surgery in 1987 at Melbourne University. He completed medical oncology training in Melbourne and worked as the Senior Clinical Research Registrar at Guy’s Hospital, London.
In 1998 arrived in Albury-Wodonga and established a medical oncology practice and clinical trials unit which has developed expertise and infrastructure to ensure the initiation of high quality trials. The research Unit lead by Dr Underhill has twice been awarded NSW Premier’s Award for Innovation in Cancer Clinical Trials, the inaugural award in 2009 and then again in 2012.
Dr Underhill is the VCCC Regional Oncology Lead and advocates for the increased access to clinical trials for regional Victorians and leads the VCCC teletrials program.
You can find Craig on X/Twitter here: @CraigUnderhill
Kate Clarke
Dr. Kate Clarke
Dr Kate Clarke (MBChB (Otago), FRACP) is a proud New Zealander with a real love for beautiful Aotearoa. Dr Clarke continues to work at being Tangata Tiriti. Much of her research and patient advocacy has an equity focus. Dr Clarke is grateful to her patients, students, whanau and colleagues for the knowledge and awhi they share. Ehara taku toa, he takitahi, he toa takitini.
Dr Clarke completed her medical training in Otago, Wellington and London. She has a holistic approach and is passionate about patient-centred care, and believes patients can and should play an active role in their healthcare. Her clinical experience covers a broad range of solid tumour malignancies with special clinical interest in colorectal cancer, upper gastrointestinal cancers and breast cancer.
Chris ‘CJ’ Jackson
Professor Christopher Jackson
Chris Jackson is Professor of Medical Oncology at the University of Otago, Dunedin, and a medical oncologist at Dunedin Hospital and Mercy Cancer Care. He specialises in GI cancers and melanoma, teaches medical students and specialists-in-training, and is heavily involved in both national and international cancer policy, leadership and research.
He was previously the medical director of the Cancer Society of NZ, and his advocacy led to the funding of new cancer drugs, to the development of a new national cancer plan, and to the birth of the national cancer agency Te Aho o Te Kahu. He currently chairs the agency’s clinical committee and serves on the advisory board. In addition, he is on the programme board of the International Cancer Benchmarking Project, and is a founding member of the Common Sense Oncology movement.
Chris is a self-confessed Radiohead tragic, and recent convert to Crossfit (even though you didn’t ask).
Connect with CJ on X/Twitter: @drkiwicj
GUESTS:
Dr Jenny Liu
Dr Jia (Jenny) Liu (MD PhD FRACP) is a full time medical oncology staff specialist at The Kinghorn Cancer Centre, St Vincent’s Hospital (Darlinghurst, Sydney Australia) specialising in head and neck cancer and the translational lead of early phase clinical trials. She supervises biomarker-directed trials including several investigator-initiated trials, with close collaborations with scientists at the Garvan Institute and ProCan Children’s Medical Research Institute, Westmead. She is also passionate about wellbeing in the oncology profession in her role as former Chair of the NSW medical oncology AT Committee and MOGA executive member and established the NOMP with Udit in 2022.
Social media: X @JiaJennyLiu LinkedIn: Jia (Jenny) Liu
Dr Nindra is a Medical Oncologist at the Illawarra Shoalhaven Local Health District in NSW, Australia.
PRODUCER:
Rachael Babin
Rachael Babin is Host of The Oncology Podcast, Editor-in-Chief of The Oncology Newsletter, and Publisher of Oncology News Australia and The Oncology Network.
With a background in oncology communications and academic publishing, Rachael is happiest sitting behind the mic chatting to interesting people about the impact their work makes in oncology.
Connect on Twitter: @OncologyNewsAus
