The Oncology Journal Club Episode 7

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Today’s episode includes an in-depth review of two key papers plus Quick Bites including a paper that asks if tweeting improves citations. We also have highlights from a very special interview with Assistant Professor David Fajgenbaum, author of the book Chasing My Cure: A Doctor’s Race to Turn Hope Into Action, who delivered the Guest Speaker’s Address at the ASCO 2020 Virtual Meeting Opening Session.

We have taken an old concept and updated it with a new format. In each episode a team of expert contributors will review topical journal papers and interview special guests who are leaders in their fields to help keep you informed of the latest developments on the go.

With The Oncology Podcast – and The Oncology Journal Club in particular – we are aiming to deliver oncology news differently,” Rachael Babin, Editor-in-Chief, Oncology News.

Today’s episode is hosted by Professor Eva Segelov, from Monash University. Eva is joined by Dr Craig Underhill from Albury-Wodonga and Professor Hans Prenen from Antwerp, Belgium. We hope you enjoy listening and find this a valuable and entertaining resource. Please let us know what you think!

This Week’s Papers:

Main Papers:

  1. de Groot, S. et al. Fasting mimicking diet as an adjunct to neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial. Nat Commun 11, 3083 (2020). Access online here.

  2. Nyberg, Kara. Stunning Progress Achieved in Lung Cancer Treatment Over the Last Decade. Lung Cancer IASLC News. Access online here.

Guest Interview:

In today’s episode we have highlights from our interview with Assistant Professor David Fajgenbaum MD, MBA, MSc. If you enjoy it, you can listen to the full interview soon!

Quick Bites:

  1. Luc JGY, et al. Does Tweeting Improve Citations? One-Year Results from the TSSMN Prospective Randomized Trial [published online ahead of print, 2020 Jun 3]. Ann Thorac Surg. 2020;S0003-4975(20)30860-2. Access online here.
  2. Babic A,  et al. Association Between Breastfeeding and Ovarian Cancer Risk [published online ahead of print, 2020 Apr 2]. JAMA Oncol. 2020;6(6):e200421. Access online here.
  3. Dolladille C et al. Immune Checkpoint Inhibitor Rechallenge After Immune-Related Adverse Events in Patients With Cancer [published online ahead of print, 2020 Apr 16]. JAMA Oncol. 2020;6(6):1-7. Access online here. 
  4. Rusthoven CG et al. Evaluation of First-line Radiosurgery vs Whole-Brain Radiotherapy for Small Cell Lung Cancer Brain Metastases: The FIRE-SCLC Cohort Study [published online ahead of print, 2020 Jun 4][published correction appears in doi: 10.1001/jamaoncol.2020.3404]. JAMA Oncol. 2020;6(7):1028-1037. Access online here.

This Week’s Team:

Professor Eva Segelov

Eva Segelov

Professor Eva Segelov is a Medical Oncologist and is Director of Oncology at Monash University and Monash Health, Melbourne, Victoria, previously Senior Medical Oncologist at St Vincent’s Hospital, St Vincent’s Private Hospital and St Vincent’s Clinic and Associate Professor of Medicine, University of New South Wales.

Eva has an interest in academic clinical trials in GI and breast cancer and has been a member of the AGITG since 2003. She has clinical trials expertise, links with national and international trials groups, and extensive experience with adult medical education.

Professor Hans Prenen

Hans Prenen

Professor Hans Prenen is a medical oncologist and head of the phase 1 – early clinical trials unit at the Antwerp University Hospital in Belgium. He is a member of several scientific organisations, published many scientific oncology papers in prestigious journals and is regularly invited for lectures at national and international meetings.  His interests are clinical trials and translational research with a focus on digestive oncology.


Dr Craig Underhill

Craig Underhill

Dr Craig Underhill completed his Bachelor of Medicine and Surgery in 1987 at Melbourne University. He completed medical oncology training in Melbourne and worked as the Senior Clinical Research Registrar at Guy’s Hospital, London.

In 1998 arrived in Albury-Wodonga and established a medical oncology practice and clinical trials unit which has developed expertise and infrastructure to ensure the initiation of high quality trials. The research Unit lead by Dr Underhill has twice been awarded NSW Premier’s Award for Innovation in Cancer Clinical Trials, the inaugural award in 2009 and then again in 2012.

Dr Underhill chaired a working party that was instrumental in securing $65 million in federal funding for The Albury Wodonga Regional Cancer Centre which opened in September 2016.

Dr Underhill is the VCCC Regional Oncology Lead and advocates for the increased access to clinical trials for regional Victorians and leads the VCCC teletrials program.

David Fajgenbaum

David Fajgenbaum, MD, MBA, MSc, is a groundbreaking physician-scientist, disease hunter, speaker and author of the bestselling memoir, Chasing My Cure: A Doctor’s Race to Turn Hope Into Action.

Known as the ‘doctor who cured himself’, Fajgenbaum went from being a college Quarterback to receiving his last rites while in medical school and nearly dying four more times battling Castleman disease. To try to save his own life, he spearheaded an innovative approach to research through the Castleman Disease Collaborative Network (CDCN) and discovered a possible treatment that has put him into an extended remission.

You can now get David’s book from Amazon Australia and from other good booksellers – there are links on David’s website here.

Rachael Babin

Rachael Babin

Rachael Babin is Editor-in-Chief of The Oncology Newsletter and Publisher of For regular oncology updates for healthcare professionals, please subscribe to The Oncology Newsletter.

With thanks to Eva Segelov, Craig Underhill, Hans Prenen, David Fajgenbaum and Graham Knowles.




About Author

The ONA Editor curates oncology news, views and reviews from Australia and around the world for our readers. In aggregated content, original sources will be acknowledged in the article footer.

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