The Oncology Journal Club Episode 2

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The Oncology Podcast, brought to you by, is proud to present the next episode in our new series – The Oncology Journal Club. Today’s episode includes an depth review of two key papers plus Quick Bites including a paper on the effects of watching Disney movies during chemotherapy, and a preview of what’s hot at ASCO.

We have taken an old concept and updated it with a new format. In each episode a team of expert contributors will review topical journal papers and studies presented at key meetings to help keep you informed of the latest developments on the go.

With The Oncology Podcast – and The Oncology Journal Club in particular – we are aiming to deliver oncology news differently,” Rachael Babin, Editor-in-Chief, Oncology News.

Today’s episode is presented by Professor Eva Segelov, from Monash University. Eva is joined by Dr Craig Underhill from Albury-Wodonga and Professor Hans Prenen from Antwerp, Belgium. We hope you enjoy listening and find this a valuable resource. Please let us know what you think!

This Week’s Papers:

Main Papers:

  1. Finn, Richard S. Finn, et al. Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma.May 14, 2020, N Engl J Med 2020. Access online here.
  2. Shu, Catherine A, et al. Neoadjuvant atezolizumab and chemotherapy in patients with resectable non-small-cell lung cancer: an open-label, multicentre, single-arm, phase 2 trial. The Lancet Oncology, May 07, 2020. Access online here.

Quick Bites:

  1. Miyamoto,Shingo, et al. Low-Dose Erlotinib Treatment in Elderly or Frail Patients With EGFR Mutation–Positive Non–Small Cell Lung Cancer: A Multicenter Phase 2 Trial. Geriatrics, JAMA Oncology, JAMA Network. Access online here.
  2. Frank, Sophie, et al. Impact of age at diagnosis of metastatic breast cancer on overall survival in the real-life ESME metastatic breast cancer cohort. The Breast, 52, 2020. Access online here.
  3. Halil Sahin, Ibrahim et al. Safety and Efficacy of Immune Checkpoint Inhibitors in Patients With Cancer Living With HIV: A Perspective on Recent Progress and Future Need. JCO Oncology Practice. Access online here.
  4. Duffy,Stephen W., et al. Mammography screening reduces rates of advanced and fatal breast cancers- results in 549091 women. Cancer, 11 May 2020. Access online here.
  5. Pils, Sophie, et al. Effect of Viewing Disney Movies During Chemotherapy on Self-Reported Quality of Life Among Patients With Gynecologic Cancer: A Randomized Clinical Trial. JAMA Network Open, Obstetrics and Gynecology, May 11, 2020. Access online here.

Recommendations for ASCO:

  1. Hans Recommends:
    GI Stream Abstracts: 4001 / 4004 / 4005 / 4006 / 4500 / 4501 / 4502
  2. Craig Recommends – GU and Lung Streams:
    Non-Small Cell Metastatic Lung Cancer Oral Session
    Lung Cancer – Non-Small Cell Local-Regional/Small Cell/Other Thoracic Cancers Oral Session
    Genitourinary Cancer – Kidney and Bladder Oral Session 
  3. Eva Recommends: 
    Plenary Session: Abstracts LBA1 / LBA4 (Keynote 177) / LBA5
    Geriatric Oncology abstracts
    Breast Oral Session
    Gynecologic Cancer Session
    Smoking cessation (SC) and lung cancer (LC) outcomes: Abstract 1512

This Week’s Team:

Professor Eva Segelov

Eva Segelov

Professor Eva Segelov is a Medical Oncologist and is Director of Oncology at Monash University and Monash Health, Melbourne, Victoria, previously Senior Medical Oncologist at St Vincent’s Hospital, St Vincent’s Private Hospital and St Vincent’s Clinic and Associate Professor of Medicine, University of New South Wales.

Eva has an interest in academic clinical trials in GI and breast cancer and has been a member of the AGITG since 2003. She has clinical trials expertise, links with national and international trials groups, and extensive experience with adult medical education.

Professor Hans Prenen

Hans Prenen

Professor Hans Prenen is a medical oncologist and head of the phase 1 – early clinical trials unit at the Antwerp University Hospital in Belgium. He is a member of several scientific organisations, published many scientific oncology papers in prestigious journals and is regularly invited for lectures at national and international meetings.  His interests are clinical trials and translational research with a focus on digestive oncology.


Dr Craig Underhill

Craig Underhill

Dr Craig Underhill completed his Bachelor of Medicine and Surgery in 1987 at Melbourne University. He completed medical oncology training in Melbourne and worked as the Senior Clinical Research Registrar at Guy’s Hospital, London.

In 1998 arrived in Albury-Wodonga and established a medical oncology practice and clinical trials unit which has developed expertise and infrastructure to ensure the initiation of high quality trials. The research Unit lead by Dr Underhill has twice been awarded NSW Premier’s Award for Innovation in Cancer Clinical Trials, the inaugural award in 2009 and then again in 2012.

Dr Underhill chaired a working party that was instrumental in securing $65 million in federal funding for The Albury Wodonga Regional Cancer Centre which opened in September 2016.

Dr Underhill is the VCCC Regional Oncology Lead and advocates for the increased access to clinical trials for regional Victorians and leads the VCCC teletrials program.

Rachael Babin

Rachael Babin

Rachael Babin is Editor-in-Chief of The Oncology Newsletter and Publisher of For regular oncology updates for healthcare professionals, please subscribe to The Oncology Newsletter.

With thanks to Eva Segelov, Craig Underhill, Hans Prenen and Graham Knowles.




About Author

ONA Editor

The ONA Editor curates oncology news, views and reviews from Australia and around the world for our readers. In aggregated content, original sources will be acknowledged in the article footer.

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