Investigational combo therapy shows benefit for TP53 mutant MDS and AML patients
Myelodysplastic Syndromes (MDS) and acute myeloid leukaemia (AML) are rare haematologic malignancies of the bone…
Browsing: TP53
Large international study pinpoints impact of TP53 gene mutations on blood cancer severity
Considered the “guardian of the genome,” TP53 is the most commonly mutated gene in cancer.…
Does evidence support BRCA1/2 and other genetic testing for patients with breast cancer?
Should germline genetic testing be offered to all patients with breast cancer? The American College…
What elephants teach us about cancer prevention
Joshua Schiffman, University of Utah and Lisa Abegglen, University of Utah Every time a cell…
AACR 2017: Many childhood cancer survivors carry mutations in cancer risk genes, raising chance of later disease
Whole-genome sequencing conducted on a large cohort of childhood cancer survivors indicated that many survivors…
Cancer-preventing protein finds its own way in our DNA
Geneticists from KU Leuven, Belgium, have shown that tumour protein TP53 knows exactly where to…