Inhibitor of KRAS gene mutation shows promise in lung, bowel and other solid tumours
New results from early clinical trials of a drug that targets a cancer-causing mutation in…
Browsing: gene mutation
Identified gene mutations impact on the severity of a type of haematologic cancer
The Myelodysplastic Syndromes Group of Josep Carreras Leukaemia Research Institute, Spain, led by Dr. Francesc…
Large international study pinpoints impact of TP53 gene mutations on blood cancer severity
Considered the “guardian of the genome,” TP53 is the most commonly mutated gene in cancer.…
FDA approves selpercatinib for lung and thyroid cancers with RET gene mutations or fusions
The Food and Drug Administration (FDA) granted accelerated approval to selpercatinib for the following indications:…
Researchers identify new gene mutation in familial thyroid cancers
Researchers from Penn State College of Medicine identified a new gene mutation that may cause…
Prostate cancer patients with gene mutation at three times the risk of dying
Scientists have identified a gene mutation in the tumours of men with prostate cancer that…
Altered gene regulation is more widespread in cancer than expected
A large-scale study provides new insights into the mechanisms that can lead to cancer. It…
RB1 gene mutations underlie clinical resistance to CDK 4/6 inhibitor breast cancer therapy
A multi-institutional research team has identified what may be a novel mechanism underlying acquired resistance…