New recommendations on genetic testing for prostate cancer
A key area impacting prostate cancer risk and treatment is germline genetic testing, which involves…
Browsing: BRCA1
Major trial shows breast cancer drug can hit prostate cancer Achilles heel
A drug already licensed for the treatment of breast and ovarian cancers is more effective…
Mayo researchers recommend all women with breast cancer diagnosis under age 66 be offered genetic testing
A study by researchers at Mayo Clinic, USA, published this week in the Journal of…
Both BRCA1-wild type and mutant triple-negative breast cancers show
Oncotarget features “MLN4924 treatment induces DNA damage by stabilising CDT1 and accumulates the cells in S…
Study finds inflammation caused by radiation can drive triple-negative breast cancer
While radiation is successfully used to treat breast cancer by killing cancer cells, inflammation caused…
AACR 2019: PARP inhibitors can shrink tumours in pancreatic cancer patients with specific mutations
Switching pancreatic cancer patients to the PARP inhibitor rucaparib as maintenance therapy instead of continuing…
BRCA1 as a stress coach in neuroblastoma
Anyone who has ever studied the molecular basis of breast cancer will probably have heard…
Gene-editing technique CRISPR identifies dangerous breast cancer mutations
Jay Shendure, University of Washington; Greg Findlay, University of Washington, and Lea Starita, University of…
Paper identifies genes associated with risk for aggressive breast cancer
A new study published in the Journal of the National Cancer Institute has identified specific genes associated…
Improving survival in pancreatic cancer with platinum-based chemotherapy
A small study of adults with the most common form of pancreatic cancer adds to…