Mayo researchers recommend all women with breast cancer diagnosis under age 66 be offered genetic testing
A study by researchers at Mayo Clinic, USA, published this week in the Journal of…
Browsing: BRCA1
Both BRCA1-wild type and mutant triple-negative breast cancers show
Oncotarget features “MLN4924 treatment induces DNA damage by stabilising CDT1 and accumulates the cells in S…
Study finds inflammation caused by radiation can drive triple-negative breast cancer
While radiation is successfully used to treat breast cancer by killing cancer cells, inflammation caused…
AACR 2019: PARP inhibitors can shrink tumours in pancreatic cancer patients with specific mutations
Switching pancreatic cancer patients to the PARP inhibitor rucaparib as maintenance therapy instead of continuing…
BRCA1 as a stress coach in neuroblastoma
Anyone who has ever studied the molecular basis of breast cancer will probably have heard…
Gene-editing technique CRISPR identifies dangerous breast cancer mutations
Jay Shendure, University of Washington; Greg Findlay, University of Washington, and Lea Starita, University of…
Paper identifies genes associated with risk for aggressive breast cancer
A new study published in the Journal of the National Cancer Institute has identified specific genes associated…
Improving survival in pancreatic cancer with platinum-based chemotherapy
A small study of adults with the most common form of pancreatic cancer adds to…
Ovarian cancer drug shows promise in pancreatic cancer patients with BRCA mutation
A targeted therapy that has shown its power in fighting ovarian cancer in women including…
Multigene testing replacing BRCA tests for breast cancer risk, researcher says
The use of genetic tests aimed at detecting the presence of mutations in the BRCA1…