AACR 2019: PARP inhibitors can shrink tumours in pancreatic cancer patients with specific mutations
Switching pancreatic cancer patients to the PARP inhibitor rucaparib as maintenance therapy instead of continuing…
Browsing: BRCA1
BRCA1 as a stress coach in neuroblastoma
Anyone who has ever studied the molecular basis of breast cancer will probably have heard…
Gene-editing technique CRISPR identifies dangerous breast cancer mutations
Jay Shendure, University of Washington; Greg Findlay, University of Washington, and Lea Starita, University of…
Paper identifies genes associated with risk for aggressive breast cancer
A new study published in the Journal of the National Cancer Institute has identified specific genes associated…
Improving survival in pancreatic cancer with platinum-based chemotherapy
A small study of adults with the most common form of pancreatic cancer adds to…
Ovarian cancer drug shows promise in pancreatic cancer patients with BRCA mutation
A targeted therapy that has shown its power in fighting ovarian cancer in women including…
Multigene testing replacing BRCA tests for breast cancer risk, researcher says
The use of genetic tests aimed at detecting the presence of mutations in the BRCA1…
Study links breast cancer to the body’s internal clock
For years, doctors have associated the BRCA1 and BRCA2 gene mutations with an increased risk…
When a genetic test result for breast cancer comes out of the blue
By Deborah Smith, UNSW Women newly diagnosed with breast cancer who learn they carry a…
EDC4 gene involved in familial breast cancer
An international research consortium led by Dr Jordi Surrallés, director of the Genetics Service at…