The OJC 57: Do You Mind If I Record?

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The Oncology Journal Club Episode 57: Do You Mind if I Record?

Join Eva Segelov, Craig Underhill and Hans Prenen as they chat through the latest papers.

Today’s papers are thought provoking – Craig ask’s ‘Do you mind if I record?’ Hans is focused on cell-free DNA from bile and Eva talks us through the COVID CAPTURE study.

You’ll hear details on updated antiemetics guidelines, patients’ expectations of the benefits from genomic tumour testing and the importance of a warm welcome.

In ‘The Paper That Changed My Practice’ segment – we hear from Nicola O’Neil a young medical oncologist from YOGA practicing in Perth.

This Week’s Main Papers:

  1. Gou Q, et al. Cell-free DNA from bile outperformed plasma as a potential alternative to tissue biopsy in biliary tract cancer. ESMO Open. 2021 Oct 12;6(6):100275. doi: 10.1016/j.esmoop.2021.100275. Epub ahead of print. PMID: 34653800; PMCID: PMC8517551. Access online here.
  2. Jimenez RB, et al. Do you mind if I record?: Perceptions and practice regarding patient requests to record clinic visits in oncology. Cancer. 2021 Oct 11. doi: 10.1002/cncr.33910. Epub ahead of print. PMID: 34633655. Access online here. 
  3. Prictor M, et al. Overt and covert recordings of health care consultations in Australia: some legal considerations. Med J Aust. 2021 Feb;214(3):119-123.e1. doi: 10.5694/mja2.50838. Epub 2020 Nov 1. PMID: 33131072. Access online here.
  4. Fendler, A., et al. Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study. Nat Cancer (2021). Access online here.

This Week’s Quick Bites:

  1. Chavez-MacGregor M, et al. Evaluation of COVID-19 Mortality and Adverse Outcomes in US Patients With or Without Cancer. JAMA Oncol. 2021 Oct 28. doi: 10.1001/jamaoncol.2021.5148. Epub ahead of print. PMID: 34709356. Access online here.
  2. Fountzilas C, et al. Phase Ib/II study of Cetuximab Plus Pembrolizumab in Patients with Advanced RAS wild-type Colorectal Cancer. Clin Cancer Res. 2021 Oct 13:clincanres.1650.2021. doi: 10.1158/1078-0432.CCR-21-1650. Epub ahead of print. PMID: 34645646. Access online here.
  3. Davis M, et al. MASCC antiemetics in advanced cancer updated guideline. Support Care Cancer. 2021 Dec;29(12):8097-8107. doi: 10.1007/s00520-021-06437-w. Epub 2021 Aug 16. PMID: 34398289. Access online here.
  4. van Ee B, Slaets J, et al. Satisfaction with hospital care in older patients with colorectal cancer, the importance of a warm welcome. J Geriatr Oncol. 2020 Jul;11(6):1028-1031. doi: 10.1016/j.jgo.2019.11.004. Epub 2019 Dec 4. PMID: 31810789. Access online here.
  5. Gupta A, et al. Time-Related Burdens of Cancer Care. JCO Oncol Pract. 2021 Oct 28:OP2100662. doi: 10.1200/OP.21.00662. Epub ahead of print. PMID: 34709950. Access online here.
  6. Anderson EC, et al. Patients’ Expectations of Benefits From Large-Panel Genomic Tumor Testing in Rural Community Oncology Practices. JCO Precis Oncol. 2021 Sep 29;5:PO.21.00235. doi: 10.1200/PO.21.00235. PMID: 34632254; PMCID: PMC8492376. Access online here.
  7. Schneider BJ, Naidoo J, Santomasso BD, Lacchetti C, Adkins S, Anadkat M, Atkins MB, Brassil KJ, Caterino JM, et al. Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: ASCO Guideline Update. J Clin Oncol. 2021 Nov 1:JCO2101440. doi: 10.1200/JCO.21.01440. Epub ahead of print. PMID: 34724392. Access online here.
  8. Adams RA, et al. Capecitabine Versus Active Monitoring in Stable or Responding Metastatic Colorectal Cancer After 16 Weeks of First-Line Therapy: Results of the Randomized FOCUS4-N Trial. J Clin Oncol. 2021 Sep 13:JCO2101436. doi: 10.1200/JCO.21.01436. Epub ahead of print. PMID: 34516759. Access online here.

Amazing Article of the Week:

Sons M, et al. Cross-lagged effects of voluntary job changes and well-being: A continuous time approach. J Appl Psychol. 2021 Oct 14. doi: 10.1037/apl0000940. Epub ahead of print. PMID: 34647782. Access online here.

The Paper That Changed My Practice:

Tattersall MH,et al. Consultation audio tapes: an underused cancer patient information aid and clinical research tool. Lancet Oncol. 2002 Jul;3(7):431-7. doi: 10.1016/s1470-2045(02)00790-8. PMID: 12142173. Access online here.

Other Episodes Mentioned:

The OJC 55: The Gut Microbiota, Electronic Health Records and COVID Risks

Other Resources:

OzSAGE: Visit website and Twitter @RealOzSAGE

Recording a health care consultation: Dos and don’ts

This Week’s Team:

Professor Eva Segelov

Eva Segelov

Professor Eva Segelov is a Medical Oncologist and is Director of Oncology at Monash University and Monash Health, Melbourne, Victoria, previously Senior Medical Oncologist at St Vincent’s Hospital, St Vincent’s Private Hospital and St Vincent’s Clinic and Associate Professor of Medicine, University of New South Wales.

Eva has an interest in academic clinical trials in GI and breast cancer and has been a member of the AGITG since 2003. She has clinical trials expertise, links with national and international trials groups, and extensive experience with adult medical education. You can find Eva on Twitter here: @profevasegelov

Professor Hans Prenen

Hans Prenen

Professor Hans Prenen is a medical oncologist and head of the phase 1 – early clinical trials unit at the Antwerp University Hospital in Belgium. He is a member of several scientific organisations, published many scientific oncology papers in prestigious journals and is regularly invited for lectures at national and international meetings.  His interests are clinical trials and translational research with a focus on digestive oncology. You can find Hans on Twitter here: @HPrenen


Associate Professor Craig Underhill

Craig Underhill

Associate Professor Craig Underhill completed his Bachelor of Medicine and Surgery in 1987 at Melbourne University. He completed medical oncology training in Melbourne and worked as the Senior Clinical Research Registrar at Guy’s Hospital, London.

In 1998 arrived in Albury-Wodonga and established a medical oncology practice and clinical trials unit which has developed expertise and infrastructure to ensure the initiation of high quality trials. The research Unit lead by Dr Underhill has twice been awarded NSW Premier’s Award for Innovation in Cancer Clinical Trials, the inaugural award in 2009 and then again in 2012.

Dr Underhill is the VCCC Regional Oncology Lead and advocates for the increased access to clinical trials for regional Victorians and leads the VCCC teletrials program. You can find Craig on Twitter here: @CraigUnderhill 

Dr Nicola O’Neil

Nicola O’Neil

Nicola completed her oncology training at Nepean, Westmead and Blacktown Hospital in Western Sydney, NSW. She relocated to Perth in 2020 and completed a fellowship in breast cancer at the Breast Cancer Research Centre-WA. She was the inaugural clinical trials fellow at Fiona Stanley Hospital in 2021. Nicola was awarded Fellow of the Royal Australasian College of Physicians in 2021.

Nicola has an interest in familial cancer syndromes and cancer genetics. She has been successfully awarded a WA Cancer and Palliative Care Network Cancer Fellowship for 2022 to undertake clinical genetics training at the Genetics Services of WA.

Rachael Babin

Rachael Babin is Editor-in-Chief of The Oncology Newsletter, Publisher of Oncology News Host of The Oncology Podcast and Producer of The Oncology Journal Club. For regular oncology updates for healthcare professionals, please subscribe to The Oncology Newsletter.

With thanks to Eva Segelov, Craig Underhill, Hans Prenen, Nicola O’Neil and Graham Knowles.

Connect with us on Twitter @OncologyNewsAus


About Author

The ONA Editor curates oncology news, views and reviews from Australia and around the world for our readers. In aggregated content, original sources will be acknowledged in the article footer.

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