New 3-D model of a DNA-regulating complex in human cells provides cancer clues
Scientists have created an unprecedented 3-dimensional structural model of a key molecular “machine” known as…
Browsing: Genetics
Genomic study of 6000 NCI-MATCH cancer patients leads to new clinical trial benchmarks
Five years ago, the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) and National Cancer Institute (NCI), part…
Researchers discover drug resistance mechanism in leukemia, ID treatment strategy
Like packaging designed to create a protective environment around a product, the mix of cells…
Aggressive childhood cancer could be treated by combining DNA-damage targeting drugs
An aggressive form of the childhood cancer neuroblastoma could be treatable with two cancer drugs currently…
Study finds cancer mutations accumulate in distinct regions based on structure of genome and mutational causes
A new study from researchers at The University of Texas MD Anderson Cancer Center, USA,…
New drug targeting DNA repair shows promise in range of advanced cancers
A new precision drug which stops cancer from repairing its DNA has shown promise in…
New insights into colorectal cancer: Growth factor R-spondin suppresses tumour growth
Colorectal cancer constitute the third most common cancer in the Western world. Their incidence constantly…
Scientists identify dozens of genes allowing cancer cells to evade the immune system
182 genes identified that regulate the interaction between cancer and immune T cells and which…
Why some cancers may respond poorly to key drugs discovered
Patients with BRCA1/2 mutations are at higher risk for breast, ovarian and prostate cancers that…
Algorithms uncover cancers’ hidden genetic losses and gains
Understanding the specific mutations that contribute to different forms of cancer is critical to improving…